Drug Discovery World (DDW)

Immunotherapy - Knocking Out Cancer With a One-Two Punch

Immunotherapy - Knocking Out Cancer With a One-Two Punch

New immunotherapies that integrate innate and adaptive immune responses may increase efficacy against many cancers, and have the potential to expand the range of tumours and patients that can be treated with immunotherapy. Over the past decade, insights into the molecular mechanisms that cancer cells use to evade T-cells, antibodies/B cells and other adaptive immune defences have revolutionised oncology therapies. New understandings of how cancer evades innate immune defences – including macrophages, dendritic cells (DC) and Natural Killer (NK) cells – suggest a second, and perhaps even more significant, immunotherapy revolution may be at hand. Original article by Dr Mark Chao, Dr Ranjana Advani, and Dr Jens Peter Volkmer If you'd like to view the original article then follow the link below: https://www.ddw-online.com/therapeutics/p322916-knocking-out-cancer-with-a-one-two-punch.html You can also download the original article pdf here: https://www.ddw-online.com/media/32/136062/(2)-knocking-out-cancer.pdf For more information on Drug Discovery World, head to: https://www.ddw-online.com

Duration: 19 min

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